
During a median follow-up of 7.6 (interquartile range 4.1-11.7) years, 42 patients underwent liver transplantation, and 127 patients died. Prediction accuracy was assessed by comparing predicted survival and actual survival in Kaplan-Meier analyses.Ī total of 1,100 ursodeoxycholic acid-treated patients with PBC were included, with a mean (SD) age of 53.6 (12.0) years, of whom 1,003 (91%) were female. Model for End-stage Liver Disease was included for comparison. The discriminatory performance of the scores was assessed with concordance statistics at yearly intervals up to 5 years. Ursodeoxycholic acid-treated patients from 7 centers participating in the GLOBAL PBC Study Group were included. We aimed to assess and compare the prognostic value of the Mayo Risk Score (MRS, 19), UK-PBC score, and GLOBE score in a large international cohort of patients with PBC. 12 Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto, Ontario, Canada.Ĭomparative data on scores that predict outcome in primary biliary cholangitis (PBC) are scarce.11 Department of Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium.10 Division of Gastroenterology and Center for Autoimmune Liver Diseases, Department of Medicine and Surgery, University of Milano-Bicocca, San Gerardo Hospital, Monza, Italy.9 Liver Unit, Hospital Clínic, CIBERehd, IDIBAPS, University of Barcelona, Barcelona, Spain.8 Arizona State University, Phoenix, Arizona, USA.7 Department of Gastroenterology and Hepatology, Ghent University Hospital, Ghent, Belgium.6 Department of Medicine and Research Laboratory of Internal Medicine, National Expertise Center of Greece in Autoimmune Liver Diseases, General University Hospital of Larissa, Larissa, Greece.5 Department of Internal Medicine III, University Hospital RWTH Aachen, Aachen, Germany.4 Department of Internal Medicine IV, Jena University Hospital, Friedrich Schiller University, Jena, Germany.3 Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy.


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Goossen works full time as a Southern California-based boxing trainer who rose to prominence guiding some of the sport’s best boxers, including the Ruelas brothers Gabriel and Rafael, to world titles. Joe Goossen works as a FOX Sports analyst calling Premier Boxing Champions (PBC) boxing fights live on FOX.
